A 21 year old woman was referred after MRI of the sella showed a pituitary microadenoma. The patient spoke very limited English.
She described a history of primary amenorrhea investigated in China and treated with the oral contraceptive pill. She also had hypothyroidism treated with levothyroxine and was on a “daily hormone injection”. She is currently off all treatments.
Physical examination was unremarkable.
Labs are as follows:
- Prolactin 38
- TSH 10
- free T4 12
- GH 0.5
- IGF-1 pending
- LH 25
- FSH 40
- estradiol < 40
- cortisol 380
What is/are the likeliest diagnosis(ses)?